Crystal Palace will begin their Premier League campaign at home to Southampton after the fixtures for the 2020-21 season were confirmed on Thursday.
The Saints will visit Selhurst Park on September 12 before Palace head to Old Trafford seven days later to face Manchester United.
Roy Hodgson's side also go to Chelsea on October 3 before hosting fierce rivals Brighton two weeks later.
Palace are due to travel to the Amex Stadium for the return fixture on February 20, while a difficult end to the season sees them face, Leicester, Manchester City, Arsenal and Liverpool in their final six games.
The Eagles head towards the new season hoping for more consistency after the highs and lows of an injury-plagued, gruelling 2019-20, which saw them eventually finish down in 14th but comfortably clear of any relegation danger.
Former West Brom full-back Nathan Ferguson has been the only arrival at Selhurst Park so far this summer as Palace bide their time in an uncertain market, though Hodgson will be hoping for several new additions over the coming weeks as he looks to add more youth to the top-flight's oldest squad.
A repeat of the injury problems faced last term during what promises to be a hectic new campaign could cause real issues if further signings are not forthcoming, with the games set to come thick and fast once more as a result of the delayed start caused by coronavirus and the rescheduled European Championship.
Palace - who are facing yet more uncertainty over the future of star player Wilfried Zaha - will also no doubt hope that fans can return sooner rather than later during the new season as they look to regain some of that lost atmosphere in SE25.
Here are Crystal Palace's full fixtures for the 2020-21 season…
| 12/09/20 | Southampton | (h) | 15:00 | |
| 19/09/20 | Manchester United | (a) | 15:00 | |
| 26/09/20 | Everton | (h) | 15:00 | |
| 3/10/20 | Chelsea | (a) | 15:00 | |
| 17/10/20 | Brighton | (h) | 15:00 | |
| 24/10/20 | Fulham | (a) | 15:00 | |
| 31/10/20 | Wolverhampton | (a) | 15:00 | |
| 7/11/20 | Leeds United | (h) | 15:00 | |
| 21/11/20 | Burnley | (a) | 15:00 | |
| 28/11/20 | Newcastle United | (h) | 15:00 | |
| 5/12/20 | West Bromwich Albion | (a) | 15:00 | |
| 12/12/20 | Tottenham Hotspur | (h) | 15:00 | |
| 15/12/20 | West Ham United | (a) | 19:45 | |
| 19/12/20 | Liverpool | (h) | 15:00 | |
| 26/12/20 | Aston Villa | (a) | 15:00 | |
| 28/12/20 | Leicester City | (h) | 15:00 | |
| 2/01/21 | Sheffield United | (h) | 15:00 | |
| 12/01/21 | Arsenal | (a) | 19:45 | |
| 16/01/21 | Manchester City | (a) | 15:00 | |
| 27/01/21 | West Ham United | (h) | 20:00 | |
| 30/01/21 | Wolverhampton | (h) | 15:00 | |
| 3/02/21 | Newcastle United | (a) | 19:45 | |
| 6/02/21 | Leeds United | (a) | 15:00 | |
| 13/02/21 | Burnley | (h) | 15:00 | |
| 20/02/21 | Brighton | (a) | 15:00 | |
| 27/02/21 | Fulham | (h) | 15:00 | |
| 6/03/21 | Tottenham Hotspur | (a) | 15:00 | |
| 13/03/21 | West Bromwich Albion | (h) | 15:00 | |
| 20/03/21 | Manchester United | (h) | 15:00 | |
| 3/04/21 | Everton | (a) | 15:00 | |
| 10/04/21 | Chelsea | (h) | 15:00 | |
| 17/04/21 | Southampton | (a) | 15:00 | |
| 24/04/21 | Leicester City | (a) | 15:00 | |
| 1/05/21 | Manchester City | (h) | 15:00 | |
| 8/05/21 | Sheffield United | (a) | 15:00 | |
| 12/05/21 | Aston Villa | (h) | 20:00 | |
| 15/05/21 | Arsenal | (h) | 15:00 | |
| 23/05/21 | Liverpool | (a) | 16:00 |
Dates and times may change due to television and cup requirements.
